Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass (JIB-to-RYGB)

This study has been completed.
Information provided by:
University of California, San Francisco Identifier:
First received: December 26, 2009
Last updated: December 28, 2009
Last verified: December 2009

This study objectives are the following.

  • To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
  • To analyze the feasibility, safety, and efficacy of one-stage laparoscopic re-operative gastric bypass surgery for failed and/or complicated Jejunoileal bypass (JIB) for weight loss.
  • To determine what factors or strategies are associated with a successful outcome. In particular, the completion of the surgery in one stage with a laparoscopic approach.

Clinically Severe Obesity
Metabolic Complications After Jejunoileal Bypass
Nutritional Complications After Jejunoileal Bypass
Obesity Recidivism
Inadequate Initial Weight Loss
Intestinal Malabsorptive Syndrome
Protein Malnutrition

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: One-stage Laparoscopic Revision of Failed and/or Complicated Jejunoileal Bypass to Roux-en-Y Gastric Bypass

Resource links provided by NLM:

Further study details as provided by University of California, San Francisco:

Primary Outcome Measures:
  • Morbidity and mortality [ Time Frame: throughout follow-up ] [ Designated as safety issue: Yes ]
  • Weight loss expressed as Body Mass Index and Percentage excess weight loss [ Time Frame: throughout follow-up ] [ Designated as safety issue: No ]
  • Remission or improvement of symptoms and JIB-related complications [ Time Frame: throughout follow-up ] [ Designated as safety issue: No ]
  • Remission or improvement of other comorbidities [ Time Frame: throughout follow-up ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Operative time [ Time Frame: transoperatively ] [ Designated as safety issue: No ]
  • conversion to open approach [ Time Frame: transoperatively ] [ Designated as safety issue: No ]
  • Hospital stay [ Time Frame: same hospitalization ] [ Designated as safety issue: No ]

Enrollment: 4
Study Start Date: December 2008
Study Completion Date: December 2009
Primary Completion Date: December 2009 (Final data collection date for primary outcome measure)
Failed / complicated jejunoileal bypass

  Show Detailed Description


Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients who underwent laparoscopic revision of JIB to Roux-en-Y gastric bypass (RYGB) for poor weight loss or JIB-related late complications were analyzed. Failed or JIB-related late complications, mostly metabolic, were considered for surgical intervention after optimized medical multidisciplinary management

Inclusion Criteria:

  • Met NIH criteria for weight loss surgery with poor weight loss after JIB
  • Intractable, severe and/or recurrent JIB-related late complications after optimized medical management
  • Laparoscopic approach for primary revisional bariatric surgery

Exclusion Criteria:

  • Any other type of revisional bariatric procedure
  • Open approach for revision surgery
  • missing records and/or unreachable patients with scant information for analysis
  Contacts and Locations
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Please refer to this study by its identifier: NCT01040533

United States, California
UCSF Fresno Center for Medical Education and Research, Department of Surgery
Fresno, California, United States, 93701
Sponsors and Collaborators
University of California, San Francisco
Study Director: Francisco M Tercero, MD Research Associate, University of California San Francisco
Principal Investigator: Kelvin D Higa, MD Professor of Surgery, University of California San Francisco
  More Information

Additional Information:

Responsible Party: Kelvin D Higa, MD; FACS; FASMBS; Professor of Surgery, University of California San Francisco, UCSF Fresno / ALSA Medical Group, Inc. Minimally Invasive Surgery Program Identifier: NCT01040533     History of Changes
Other Study ID Numbers: CMC IRB No. 2008085  U1111-1112-9885 
Study First Received: December 26, 2009
Last Updated: December 28, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, San Francisco:
Failed jejunoileal bypass
Complicated jejunoileal bypass
Revision gastric bypass
Revisional surgery
Metabolic and nutritional complications

Additional relevant MeSH terms:
Obesity, Morbid
Weight Loss
Body Weight
Body Weight Changes
Nutrition Disorders
Severe Acute Malnutrition
Signs and Symptoms processed this record on May 30, 2016