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Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

This study has been completed.
Sponsor:
Information provided by:
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT00018356
First received: July 3, 2001
Last updated: June 22, 2011
Last verified: June 2011
History of Changes
  Purpose

This study's primary objective is to determine the independent and combined effects of progressive resistance muscle strength training and testosterone on the development of sustainable improvements in physical function.


Condition Intervention Phase
Muscle Weakness
Muscular Atrophy
 Procedure: exercise
Drug: testosterone
 Phase 4

Study Type: Interventional
Official Title: Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Department of Veterans Affairs:

Estimated Enrollment: 88
Study Start Date: January 1999
Study Completion Date: August 2006
Primary Completion Date: July 2006 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
1 Procedure: exercise Drug: testosterone

  Eligibility

Ages Eligible for Study:   65 Years and older
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

The study will be limited to those patients who are metabolically stable and free of metastatic cancer and limiting end organ disease. Their total serum testosterone must be less than 480 and PSA less than 10.

Exclusion Criteria:

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00018356

Locations
United States, Arkansas
Central Arkansas VHS Eugene J. Towbin Healthcare Ctr, Little Rock
No. Little Rock, Arkansas, United States, 72114-1706
Sponsors and Collaborators
Department of Veterans Affairs
Investigators
Principal Investigator: Dennis Sullivan, MD Central Arkansas VHS Eugene J. Towbin Healthcare Ctr, Little Rock
  More Information

Publications:

Responsible Party: Sullivan, Dennis - Principal Investigator, Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT00018356     History of Changes
Other Study ID Numbers: AGCG-007-98S
Study First Received: July 3, 2001
Last Updated: June 22, 2011
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
Aging
nutrition
rehabilitation

Additional relevant MeSH terms:
Asthenia
Muscular Atrophy
Muscle Weakness
Paresis
Atrophy
Signs and Symptoms
Neuromuscular Manifestations
Neurologic Manifestations
Nervous System Diseases
Pathological Conditions, Anatomical
Muscular Diseases
Musculoskeletal Diseases
Pathologic Processes
Testosterone
 Testosterone enanthate
Testosterone undecanoate
Testosterone 17 beta-cypionate
Methyltestosterone
Androgens
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Pharmacologic Actions
Antineoplastic Agents, Hormonal
Antineoplastic Agents
Therapeutic Uses
Anabolic Agents

ClinicalTrials.gov processed this record on May 23, 2013