Rehabilitation of Everyday Memory Impairment in Parkinson Disease: A Pilot Study (REMI-PD)

This study is currently recruiting participants.
Verified November 2011 by Washington University School of Medicine
Sponsor:
Information provided by (Responsible Party):
Erin Foster, Washington University School of Medicine
ClinicalTrials.gov Identifier:
NCT01469741
First received: November 8, 2011
Last updated: November 10, 2011
Last verified: November 2011

November 8, 2011
November 10, 2011
June 2011
December 2015   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01469741 on ClinicalTrials.gov Archive Site
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Rehabilitation of Everyday Memory Impairment in Parkinson Disease: A Pilot Study
Rehabilitation of Everyday Memory Impairment in Parkinson Disease: A Pilot Study

Cognitive impairment is common among non-demented individuals with Parkinson disease (PD) and is a significant source of disability and reduced quality of life. Unfortunately, there are no successful interventions to address these impairments. Prospective memory impairment is a particularly functionally- and clinically-relevant problem in PD. The investigator's project will determine if a targeted intervention strategy improves PD participants' prospective memory. The investigator's goal is to improve PD patients' everyday prospective memory so they can successfully perform desired activities and roles.

Cognitive impairment is common among non-demented individuals with Parkinson disease (PD) and is a significant source of disability and reduced quality of life. Unfortunately, there are no successful interventions to address these impairments. Prospective memory impairment is a particularly functionally- and clinically-relevant problem in PD. The investigator's project will determine if a targeted intervention strategy improves PD participants' prospective memory. The investigator will use a randomized controlled design and a laboratory-based assessment of prospective memory to test the effect of the strategy in a controlled environment. The investigator will also see if PD participants, with support from an occupational therapist (OT), can generalize the strategy to their complex, real-world environments and tasks. Our goal is to improve PD patients' everyday prospective memory so they can successfully perform desired activities and roles.

Interventional
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Intervention Model: Single Group Assignment
Primary Purpose: Supportive Care
Parkinson's Disease
Behavioral: Prospective Memory Strategy
Prospective memory is central to performance in everyday life as it serves to bind together goal-directed actions and enables people to carry out their plans and wishes meaningfully and appropriately. Everyday prospective memory tasks include remembering to run errands, keep appointments, and turn off the stove after using it.
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
66
Not Provided
December 2015   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Participants will be males and females over age 50 who meet criteria for idiopathic typical PD, are Hoehn & Yahr39 stage I-III (mild-moderate disease) and are treated with levodopa/carbidopa.

Exclusion Criteria:

  • Possible dementia,
  • treatment with certain medications that interfere with cognition (e.g., anticholinergics),
  • change in medications over the study period, other neurological disorders, brain surgery (e.g., STN DBS),
  • history of psychotic disorder or significant current psychiatric disorder, or any condition that would interfere with testing (e.g., vision problems).
Both
50 Years and older
No
Contact: Tasha Doty, MA 314-362-7160 dotyt@npg.wustl.edu
Contact: Erin Foster, OTD, OTR/L 314-286-1638 erfoster@wustl.edu
United States
 
NCT01469741
201103176
No
Erin Foster, Washington University School of Medicine
Washington University School of Medicine
Not Provided
Not Provided
Washington University School of Medicine
November 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP