Fatty Liver and Ectopic Fat in Overweight and Obese Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2010 by Centre Hospitalier Universitaire de Nice.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Centre Hospitalier Universitaire de Nice
ClinicalTrials.gov Identifier:
NCT00886301
First received: April 20, 2009
Last updated: March 29, 2010
Last verified: March 2010

April 20, 2009
March 29, 2010
March 2010
June 2013   (final data collection date for primary outcome measure)
Liver status will be will be determined by liver biopsy, non invasive liver assessment. Biological and medical imaging parameters will be use to characterize our patients. [ Time Frame: at inclusion and at year 1 ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00886301 on ClinicalTrials.gov Archive Site
Non invasive liver assessment, biological and medical imaging parameters will be use to characterize our patients. [ Time Frame: at year 1 ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Fatty Liver and Ectopic Fat in Overweight and Obese Patients
Fatty Liver and Ectopic Fat in Overweight and Obese Patients

The aim of the study is to find new clinico-biological and medical imaging parameters associated with non alcoholic steatohepatitis in overweight and obese patients.

Non invasive assessment of liver fibrosis and liver inflammation and steatosis is clinically relevant in patients exposed to non alcoholic fatty liver diseases.

The aim of the study is to find new clinico-biological and medical imaging parameters associated with non alcoholic steatohepatitis in overweight and obese patients.

Fatty liver and ectopic fat accumulation will be particularly assessed.

Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Steatohepatitis
Procedure: liver biopsy
liver biopsy
1
obese or overweight patients with fatty liver or ectopic fat
Intervention: Procedure: liver biopsy
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
100
June 2013
June 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • BMI between 25 and 40
  • ALAT level superior to normal level even after 3 months of diet
  • alcohol consumption < 20 g/j for women and < 30 g/j for men

Exclusion Criteria:

  • HIV, hepatitis B virus, hepatitis C virus positive
  • known hemochromatosis
  • glycemia > 1.26 g/L or under anti-diabetic treatment
Both
18 Years to 70 Years
No
Contact: Rodolphe ANTY, Dr anty.r@chu-nice.fr
Contact: Annie FAFIN 04592035943 fafin.a@chu-nice.fr
France
 
NCT00886301
08-PP-08
No
Centre Hospitalier Universitaire de Nice, Département de la Recherche Clinique et de l'Innovation
Centre Hospitalier Universitaire de Nice
Not Provided
Principal Investigator: Rodolphe ANTY, Dr Hepatogastroentérology, CHU de Nice
Centre Hospitalier Universitaire de Nice
March 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP