Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.

This study has been completed.
Sponsor:
Collaborator:
Saskatoon Health Region
Information provided by (Responsible Party):
Marilyn Baetz, University of Saskatchewan
ClinicalTrials.gov Identifier:
NCT00225459
First received: September 21, 2005
Last updated: October 4, 2011
Last verified: October 2011

September 21, 2005
October 4, 2011
June 2005
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Complete list of historical versions of study NCT00225459 on ClinicalTrials.gov Archive Site
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Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.
Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.

The purpose of this study is to determine whether or not spiritual and/or religious commitment affects mood variability and thoughts of suicide.

First we hypothesize that among patients with depressive symptoms, those who have higher religious/spiritual (R/S) commitment will have less suicidal ideation and less mood variability. Second, we hypothesize that higher mood variability will be associated with more suicidal ideation. Finally, dependent on the first two hypotheses, we propose that R/S commitment will mediate the relationship between mood variability and suicidal ideation.

The suicide rate has not changed dramatically in the recent past, despite advances in psychiatric and mental health treatment, suicide prevention and awareness programs, and reorganization of health services. Depression and the mood disorders which may affect 15% of the population are the conditions most associated with high suicide rates (in addition to psychotic conditions that are relatively rare). Research findings into specific conditions within the depressive disorders that might predict suicidal tendencies are sparse, except for other common comorbid conditions such as panic and alcohol abuse. Research into risks and protective factors has infrequently included religious and spiritual variables that have been associated with decreased rates of depression, suicide, suicide attempts and suicidal ideation.

An inverse relationship between religion and suicide has been found in regional, national, and cross-national studies. Analyzing data from the 1993 Mortality Followback Survey in the US, frequency of religious activities reduced the odds of dying by suicide even after controlling for the frequency of social contact; in 584 deaths by suicide compared with 4279 natural deaths. A Canadian study of 261 Census divisions found the absence of religious affiliation to be an important predictor of death by suicide.

There are no known studies examining mood variability and religion, or spirituality directly. A number of studies however have examined personality attributes and religiosity. The personality style of neuroticism includes moodiness and negative emotionality with the concept of mood reactivity being germane to its construct. Neuroticism is highly correlated with depression and may be a higher order factor in the "internalizing disorders" which include the depressive and anxiety disorders.

The objective of this study is to answer the question "Does R/S mediate the relationship between mood variability and suicidal ideation?" In an effort to achieve that objective, there are three questions that must be answered in this population which in themselves are significant contributions to the research literature.

  1. Is there an association between mood variability and suicidal ideation?
  2. Is there an association between mood variability and religion?
  3. Is there an association between religion and suicidal ideation?

We hypothesize that those who endorses higher religious/spiritual commitment as measured by daily spiritual experiences, positive religious coping, and personal devotion, will have less suicidal ideation, and less mood variability. Secondly, we hypothesize that higher mood variability will be associated with more suicidal ideation. Finally, dependent on the first two hypotheses, we propose that R/S commitment will mediate the relationship between mood variability and suicidal ideation.

Observational
Observational Model: Case-Crossover
Time Perspective: Prospective
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Non-Probability Sample

The study population is psychiatric inpatients and outpatients with depressive symptoms between the ages or 18 and 70. Co-morbid anxiety, bipolar spectrum, and eating disorders will be allowed. Involuntary patients and those with psychosis, organic brain impairment, and current substance dependence will be excluded. We will recruit patients prospectively, as they attend psychiatrists' clinics and are admitted to hospital.

  • Anxiety Disorder
  • Mood Disorder
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
200
December 2008
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Inclusion Criteria:

  • Inpatients and outpatients.
  • DSM-IV defined major depression.
  • Comorbid anxiety, bipolar spectrum, and schizoaffective (depressive type).
  • Males and females between the ages of 18 and 70.

Exclusion Criteria:

  • Involuntary patients.
  • In/out patients with current psychosis.
  • In/out patients with neurological impairment.
  • In/out patients with current substance dependence.
Both
18 Years to 70 Years
No
Contact information is only displayed when the study is recruiting subjects
Canada
 
NCT00225459
Beh-REB 05-18
Not Provided
Marilyn Baetz, University of Saskatchewan
University of Saskatchewan
Saskatoon Health Region
Principal Investigator: Marilyn Baetz, MD University of Saskatchewan
University of Saskatchewan
October 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP