Aerobic Exercise to Improve Executive Language Function In Older Adults
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Purpose
The purpose of this study is to see if exercise can improve brain function in older adults
| Condition | Intervention |
|---|---|
|
Aging |
Behavioral: Aerobic group Behavioral: Strength training |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
| Official Title: | Aerobic Exercise to Improve Executive Language Function in Older Adults |
- Executive Language Functions [ Time Frame: pre and post separated by 12 weeks ] [ Designated as safety issue: No ]
| Enrollment: | 50 |
| Study Start Date: | September 2010 |
| Study Completion Date: | January 2012 |
| Primary Completion Date: | January 2012 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: 1
12 weeks of aerobic exercise 3 times a week
|
Behavioral: Aerobic group
12 weeks of aerobic exercise 3 times a week
|
|
Active Comparator: 2
12 weeks of strength training 3 times a week
|
Behavioral: Strength training
12 weeks of strength training 3 times a week
|
Detailed Description:
Recently, considerable attention has been devoted to examining the beneficial relationship between cognition and aerobic exercise in older adults. Specifically, the effects are thought to involve higher order cognitive processes, such as working memory, switching between tasks, and inhibiting irrelevant information, all of which are thought to be sub- served, in part, by the frontal lobes (Colcombe et al., 2006). Importantly, these areas also are most susceptible to age-related decline (Raz, 2000) and are essential resources for language production (Kemper & Sumner, 2001; Murray & Lenz, 2001). However, despite promising cognitive improvement, changes in frontally-mediated executive language functions have been widely ignored. This is unfortunate considering impaired word retrieval compromises communicative effectiveness, leading to frustration, depression, and withdrawal. Perhaps more importantly, communication ineffectiveness, particularly in the elderly, leads to difficulties interacting with health care professionals leading to further health care burdens. Since cognition, and specifically word retrieval difficulties, usually remain untreated, it is important to find treatment strategies for minimizing these deficits. Therefore, the short-term goal and the purpose of this proposal is to examine the potential of aerobic exercise to improve executive language function in older adults.
Eligibility| Ages Eligible for Study: | 55 Years to 75 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Consent of participants' primary health care physicians to participate in the aerobic exercise.
- Patients must not have participated in any consistent exercise program or experimental study for at least 3 months prior to enrollment.
- They must be capable of providing informed consent and complying with the trial procedures.
Exclusion Criteria:
- Demented as defined by the Modified Mini Mental Status Exam.
- Unalterable travel schedules.
- Site accessibility constraints.
Contacts and Locations| United States, Florida | |
| North Florida/South Georgia Veterans Health System | |
| Gainesville, Florida, United States, 32608 | |
| Principal Investigator: | Joe R Nocera, PhD | North Florida/South Georgia Veterans Health System |
More Information
No publications provided
| Responsible Party: | Department of Veterans Affairs |
| ClinicalTrials.gov Identifier: | NCT00979069 History of Changes |
| Other Study ID Numbers: | E6860M |
| Study First Received: | September 15, 2009 |
| Last Updated: | January 27, 2012 |
| Health Authority: | United States: Federal Government |
ClinicalTrials.gov processed this record on May 19, 2013