Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis
In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history regarding allergic diseases, exposition to passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick Tests will be performed. In this study the investigators will evaluate lung function parameters (spirometry with bronchial reversibility test and exercise induced bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature, nasal cytology.
The aim of the study will be to evaluate possible correlation between these different parameters and clinical status of the patients.
|Study Design:||Observational Model: Case-Only
Time Perspective: Cross-Sectional
|Official Title:||Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis|
- Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis [ Time Frame: Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis ] [ Designated as safety issue: Yes ]
|Study Start Date:||July 2009|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2013 (Final data collection date for primary outcome measure)|
|asthma and rhinitis control||
Other: regular treatment
Other Name: asthma treatment
Each patients will be evaluated by spirometry and then he will undergo exercise challenge in order to evaluate exercise-induced bronchoconstriction as a marker of asthma control. The test of the challenge will be correlate with childhood Asthma control test score,levels of control (GINA classification)and the different markers of airway inflammation and atopy.
|Contact: Attilio Boner, MDemail@example.com|
|Pediatric department University of Verona||Recruiting|
|Verona, Italy, 37134|
|Contact: Attilio Boner, MD --390458124615 firstname.lastname@example.org|
|Principal Investigator: Attilio Boner, MD|
|Sub-Investigator: Iolanda Chinellato, MD|
|Principal Investigator:||Attilio Boner, MD||Universita di Verona|