Text Size

Magnetic Resonance Imaging (MRI) Study of the Hippocampus After Infarction in the Territory of the Middle Cerebral Artery

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2009 by Huazhong University of Science and Technology.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Huazhong University of Science and Technology
ClinicalTrials.gov Identifier:
NCT00867581
First received: March 23, 2009
Last updated: NA
Last verified: March 2009
History: No changes posted
  Purpose

The purpose of this study is to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.


Condition
Ischemic Stroke

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: To Observe Delayed Neuronal Death of Hippocampus After Middle Cerebral Artery Infarction Through Magnetic Resonance Imaging(MRI) Volume Measurement and Magnetic Resonance Spectroscopy(MRS) Study of Hippocampus

Resource links provided by NLM:

MedlinePlus related topics: MRI Scans
U.S. FDA Resources

Further study details as provided by Huazhong University of Science and Technology:

Estimated Enrollment: 80
Study Start Date: September 2008
Estimated Primary Completion Date: July 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
chronic-stage patients after infarction in the territory of unilateral middle cerebral artery
2
age, sex and risk factor matched volunteers without ischemic stroke

Detailed Description:

40 patients with middle cerebral artery infarction and 40 healthy volunteers will be observed. All of them will receive MRI scan and the assessment of the neuropsychological function (MMSE, AVLT, HAMD) intending to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

chronic-stage patients of unilateral middle cerebral artery infarction

Criteria

Inclusion Criteria:

  • Clinical diagnosis of middle cerebral artery infarction
  • At least six months from the stroke
  • Must be able to measure his(her) neuropsychologic function (by MMSE, AVLT)

Exclusion Criteria:

  • Unable to undergo examinations due to disturbances of consciousness or medical conditions
  • Severe dementia, apraxia, disturbances of sensation or perception
  • Serious complications including severe heart failure, hepatic dysfunction, renal insufficiency,or shock
  • Parkinson's disease, malignant tumor, autoimmune diseases
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00867581

Contacts
Contact: Wei Wang, Doctor 86-027-8366-3648 wwang_tjh@126.com

Locations
China, Hubei
Department of Neurology of Tongji Hospital, Huazhong University of Science and Technology Recruiting
Wuhan, Hubei, China
Contact: Wei Wang, Doctor     86-027-8366-3648     wwang_tjh@126.com    
Principal Investigator: Wei Wang, Doctor            
Sponsors and Collaborators
Huazhong University of Science and Technology
Investigators
Principal Investigator: Wei Wang, Doctor Huazhong University of Science and Technology
  More Information

No publications provided

Responsible Party: Wei Wang, Department of Neurology of Tongji Hospital, Huazhong University of Sci. and Tec
ClinicalTrials.gov Identifier: NCT00867581     History of Changes
Other Study ID Numbers: 30725019-2
Study First Received: March 23, 2009
Last Updated: March 23, 2009
Health Authority: China: Ethics Committee

Keywords provided by Huazhong University of Science and Technology:
middle cerebral artery
infarction
chronic stage
hippocampal volume
 MRI
MRS
neuropsychologic assessment

Additional relevant MeSH terms:
Infarction
Stroke
Infarction, Middle Cerebral Artery
Ischemia
Pathologic Processes
Necrosis
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
 Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Cerebral Infarction
Brain Infarction
Brain Ischemia
Cerebral Arterial Diseases
Intracranial Arterial Diseases

ClinicalTrials.gov processed this record on June 18, 2013