Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy
The purpose of this study is to compare the cardiovascular risks of growth hormone deficient young adult males who have completed growth hormone therapy to healthy young adult males.
Growth Hormone Deficiency
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy.|
- Compare carotid artery intima medial thickness [ Time Frame: During study visit ] [ Designated as safety issue: No ]
- Compare metabolic parameters and body composition measurements [ Time Frame: During study visit ] [ Designated as safety issue: No ]
|Study Start Date:||June 2008|
|Study Completion Date:||February 2009|
|Primary Completion Date:||February 2009 (Final data collection date for primary outcome measure)|
18-25 year old males, growth hormone deficient, who completed growth hormone treatment 3-5 years prior to enrollment in study
18-25 year old males, healthy, never treated with growth hormones.
Adults with growth hormone deficiency are at risk for cardiovascular disease. What age this begins is not known.
The objectives of this study are to compare the following measurements between growth hormone deficient young males 3-7 years post completion of growth hormone treatment and age related healthy controls:
- Carotid artery imaging
- Metabolic and cardiac parameters
- Body composition measurements
Please refer to this study by its ClinicalTrials.gov identifier: NCT00711061
|United States, Missouri|
|Childrens Mercy Hospitals and Clinics|
|Kansas City, Missouri, United States, 64108|
|Principal Investigator:||Carol Huseman, MD||Children's Mercy Hospital Kansas City|