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The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis

This study is currently recruiting participants.
Verified May 2006 by National Taiwan University Hospital
Sponsor:
Collaborators:
National Science Council, Taiwan
National Health Research Institutes, Taiwan
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT00509314
First received: July 29, 2007
Last updated: NA
Last verified: May 2006
History: No changes posted
  Purpose

The aim of this study is to survey melanocytes in the ability of self-assembly on biomaterials and functional analysis in vitro. Also, this study may provide a better way for treatment of vitiligo after understanding the functional aspects of melanocytes.


Condition Intervention
Melanocyte
Vitiligo
 Behavioral: melanocyte self-assembly and functional analysis

Study Type: Observational
Study Design: Additional Descriptors: Convenience Sample
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis

Resource links provided by NLM:

MedlinePlus related topics: Vitiligo
U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 400
Study Start Date: May 2006
Estimated Study Completion Date: December 2016
Detailed Description:

Vitiligo is a chronic disease that causes loss of melanocyte and pigment of the skin. Traditional treatments for vitiligo including topical corticosteroids and phototherapy lead to limited clinical effects. Autologous melanocyte transplantation is another way to treat vitiligo. However, the effect is largely affected by whether cultivated melanocytes are successfully uptaken by vitiliginous skin. The aim of this study is to survey the self-assembly on biomaterials and functional analysis. In the long run, this study may provide a better way for treatment of vitiligo.

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients receiving cosmetic removal of moles

Exclusion Criteria:

  • No special exclusion criteria
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00509314

Contacts
Contact: Sung-Jan Lin, MD PhD +886-2-23123456 ext 5323 jsjl2000tw@yahoo.com.tw

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: Sung-Jan Lin, MD PhD     +886-2-23123456 ext 5323     jsjl2000tw@yahoo.com.tw    
Principal Investigator: Sung-Jan Lin, MD PhD            
Sponsors and Collaborators
National Taiwan University Hospital
National Science Council, Taiwan
National Health Research Institutes, Taiwan
Investigators
Principal Investigator: Sung-Jan Lin, MD PhD National Taiwan University Hospital
  More Information

Publications:

ClinicalTrials.gov Identifier: NCT00509314     History of Changes
Other Study ID Numbers: 9561703036
Study First Received: July 29, 2007
Last Updated: July 29, 2007
Health Authority: Taiwan: Department of Health

Additional relevant MeSH terms:
Vitiligo
Hypopigmentation
Pigmentation Disorders
Skin Diseases

ClinicalTrials.gov processed this record on June 18, 2013