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Postanesthesia Cognitive Recovery and Neuropsychologic Complications

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2007 by University of Roma La Sapienza.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University of Roma La Sapienza
ClinicalTrials.gov Identifier:
NCT00507195
First received: July 23, 2007
Last updated: July 24, 2007
Last verified: May 2007
History of Changes
  Purpose

The study proposes to analyze the difference in the rapidity of the recovery of post operative cognition immediately after extubation and 20, 40 and 60 minutes post extubation and neuropsychological complications (delirium) after 48 hours following general anesthesia using a prospective, randomized approach. Patients undergoing any type of surgery with the exception of cranial, cardiac or thoracic surgery can be enrolled in the study.


Condition Intervention
Anesthesia Recovery Period
Delirium, Dementia, Cognitive Disorders
Neurobehavioural Manifestation
Mental Competency
 Drug: Hypnotics: propofol, sevoflurane, desflurane,desflurane,midazolam

Study Type: Observational
Study Design: Additional Descriptors: Convenience Sample
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Post Operative Cognitive Recovery and Neuropsychological Complications After General Anesthesia. A Comparison Between Different Techniques of Anesthesia: A Multi-Center Observational Study

Resource links provided by NLM:

MedlinePlus related topics: Delirium Dementia
U.S. FDA Resources

Further study details as provided by University of Roma La Sapienza:

Estimated Enrollment: 1200
Study Start Date: May 2007
Intervention Details:
    Drug: Hypnotics: propofol, sevoflurane, desflurane,desflurane,midazolam
    Other Names:
    • Propofol,
    • sevoflurane,
    • desflurane,
    • midazolam
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Adult age patients undergoing general anesthesia

Exclusion Criteria:

  • Cerebral and cardiac surgery
  • Surgical procedures required postoperative delayed extubation
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00507195

Contacts
Contact: Federico Bilotta, MD, PhD 39 339 33 708 22 bilotta@tiscali.it

Locations
Italy
Azienda Policlinico Umberto I, University of Rome La Sapienza, Recruiting
Rome,, Italy, 00161
Contact: Federico Bilotta, MD, PhD            
Principal Investigator: Federico Bilotta, MD, PhD            
Sponsors and Collaborators
University of Roma La Sapienza
Investigators
Study Chair: Federico Bilotta, MD, PhD University of Roma La Sapienza
  More Information

No publications provided by University of Roma La Sapienza

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

ClinicalTrials.gov Identifier: NCT00507195     History of Changes
Other Study ID Numbers: pinocchio
Study First Received: July 23, 2007
Last Updated: July 24, 2007
Health Authority: Italy: Ethics Committee

Keywords provided by University of Roma La Sapienza:
Postanethesia cognitive recovery
Postoperative delirium
hypnotics
propofol
 sevoflurane
desflurane
postoperative cognitive recovery

Additional relevant MeSH terms:
Cognition Disorders
Delirium
Dementia
Neurobehavioral Manifestations
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders
Confusion
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Brain Diseases
Central Nervous System Diseases
Midazolam
Hypnotics and Sedatives
Propofol
 Desflurane
Sevoflurane
Adjuvants, Anesthesia
Central Nervous System Agents
Therapeutic Uses
Pharmacologic Actions
Anti-Anxiety Agents
Tranquilizing Agents
Central Nervous System Depressants
Physiological Effects of Drugs
Psychotropic Drugs
Anesthetics, Intravenous
Anesthetics, General
Anesthetics
GABA Modulators

ClinicalTrials.gov processed this record on June 17, 2013