Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Intensive Strength Training in Children With Cerebral Palsy - Effect on Hand Function

This study has been completed.
Norwegian University of Science and Technology
Information provided by:
St. Olavs Hospital Identifier:
First received: April 27, 2007
Last updated: June 2, 2008
Last verified: April 2007

The objective of this study is to gain more knowledge about the association between muscle weakness, spasticity and motor control in children with cerebral palsy, and its relationship to hand function.

Condition Intervention Phase
Cerebral Palsy
Drug: Botulinum Toxin A
Behavioral: Strength training
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by St. Olavs Hospital:

Estimated Enrollment: 20
Study Start Date: September 2006
Study Completion Date: March 2008
Primary Completion Date: October 2007 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   10 Years to 17 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosed spastic hemiplegic or diplegic cerebral palsy, reduced handfunction.
  • Indication for treatment with Botulinum Toxin A
  • Score 3 on House Classification of Upper-Extremity Functional Use
  • Score 3 or better on Manual Ability Classification System

Exclusion Criteria:

  • surgery within the last two years
  • Treatment with Botulinum Toxin within the last six months
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00467207

St. Olavs Hospital
Trondheim, Trondheom, Norway, 7004
Sponsors and Collaborators
St. Olavs Hospital
Norwegian University of Science and Technology
Study Chair: Torarin I Lamvik, Medical doctor St. Olavs Hospital
Principal Investigator: Karin Roeleveld, Phd Norwegian University of Science and Technology
  More Information

No publications provided

Responsible Party: St. Olavs Hospital Identifier: NCT00467207     History of Changes
Other Study ID Numbers: 06/1553
Study First Received: April 27, 2007
Last Updated: June 2, 2008
Health Authority: Norway: Norwegian Social Science Data Services

Additional relevant MeSH terms:
Cerebral Palsy
Brain Damage, Chronic
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Botulinum Toxins
Botulinum Toxins, Type A
Anti-Dyskinesia Agents
Central Nervous System Agents
Neuromuscular Agents
Peripheral Nervous System Agents
Pharmacologic Actions
Physiological Effects of Drugs
Therapeutic Uses processed this record on November 25, 2014