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Influence of Thoracic Epidural Anesthesia on Skin Sympathetic Activity and Heart Rate Variability

This study has been completed.
Sponsor:
Information provided by:
University Hospital Muenster
ClinicalTrials.gov Identifier:
NCT00222391
First received: September 20, 2005
Last updated: January 6, 2009
Last verified: March 2006
History of Changes
  Purpose

The purpose of the study is to evaluate the impact of epidural anesthesia on sympathetic activity in surgical patients. The study investigates whether a segmental sympathetic block can be determined and can be correlated to level of the sensoric blockade.


Condition
Abdominal Surgery
Abdominothoracic Surgery

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Influence of Thoracic Epidural Anesthesia on Skin Sympathetic Activity and Heart Rate Variability in Surgical Patients

Further study details as provided by University Hospital Muenster:

Primary Outcome Measures:
  • Hemodynamic parameters

Secondary Outcome Measures:
  • Level of sensoric block
  • skin temperature

Estimated Enrollment: 40
Study Start Date: April 2004
Estimated Study Completion Date: January 2006
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • elective surgery
  • combined anesthesia with thoracic epidural anesthesia 8 (Th6-9
  • Body-mass-index < 30

Exclusion Criteria:

  • Fever, Hypothermia, SIRS
  • Microangiopathy
  • Neuropathy
  • Sensomotoric deficits
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00222391

Locations
Germany
Department of Anesthesia and Intensive Care, University Hospital Muenster
Muenster, Germany, D-48149
Sponsors and Collaborators
University Hospital Muenster
Investigators
Principal Investigator: Henrik Freise, MD Department of Anesthesiology and Intensive Care, University Hospital Münster
  More Information

Publications:

ClinicalTrials.gov Identifier: NCT00222391     History of Changes
Other Study ID Numbers: 01-Anast-04
Study First Received: September 20, 2005
Last Updated: January 6, 2009
Health Authority: Germany: Ethics Commission

Additional relevant MeSH terms:
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs
 Pharmacologic Actions
Central Nervous System Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on May 22, 2013