Treatment of Subclinical Hyperthyroidism

The recruitment status of this study is unknown because the information has not been verified recently.

Verified November 2007 by University Hospital, Strasbourg, France.
Recruitment status was Recruiting

Sponsor:

Information provided by (Responsible Party):

University Hospital, Strasbourg, France

ClinicalTrials.gov Identifier:

NCT00213720

First received: September 13, 2005

Last updated: April 19, 2012

Last verified: November 2007

History of Changes

Purpose

Objective: To determine if the treatment of subclinical hyperthyroidism will reduce the rate of atrial fibrillation, the main complication of this condition.

Condition	Phase
Subclinical Hyperthyroidism Atrial Fibrillation	Phase 4

Study Type:	Observational
Study Design:	Observational Model: Cohort Time Perspective: Prospective
Official Title:	Place de l'Iode RadioActif Dans l'HyperThyroïdiE Sub-clinique (PIRHATES)/ Evaluation of the Interest of Subclinical Hyperthyroidism Treatment

Resource links provided by NLM:

Genetics Home Reference related topics: familial atrial fibrillation

MedlinePlus related topics: Atrial Fibrillation

U.S. FDA Resources

Further study details as provided by University Hospital, Strasbourg, France:

Biospecimen Retention: Samples Without DNA

serum

Estimated Enrollment:	300
Study Start Date:	August 2005

Detailed Description:

Randomized open-labelled multicentre study comparing radioiodine vs medical supervision without treatment

Eligibility

Ages Eligible for Study:	50 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

patients referred to tertiary hospitals for advice on thyroïd disease

Criteria

Inclusion Criteria:

Men and women aged 50 and greater
Isolated decreased thyroid-stimulating hormone (TSH) with normal FT4 and FT3 levels

Exclusion Criteria:

Iodide overload
Non sinusal heart rhythm
Severe heart disease

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00213720

Contacts

Contact: Bernard Goichot, MD

333 88 12 75 93

bernard.goichot@chru-strasbourg.fr

Locations

France
Patrick Roger	Recruiting
Bordeaux, France
Contact: Patrick Roger, MD 335 57 65 64 33 patrick.roger@chu-bordeaux.fr
Philippe Thiéblot	Not yet recruiting
Clermont-Ferrand, France
Contact: Philippe Thiéblot, MD 334 73 75 15 33 pthieblot@chu-clermontferrand.fr
Jean-Marcel Brun	Not yet recruiting
Dijon, France
Contact: Jean-Marcel Brun 333 80 29 34 53 jean-marcel.brun@chu-dijon.fr
Jean-Louis Wemeau	Recruiting
Lille, France
Contact: Jean-Louis Wemeau, MD 333 20 44 41 18 jl-wemeau@chru-lille.fr
Marie-Pierre Teissier	Recruiting
Limoges, France
Contact: Marie-Pierre Teissier, MD 335 55 05 68 51 marie-pierre.teissier@chu-limoges.fr
Jacques Orgiazzi	Recruiting
Lyon, France
Contact: Jacques Orgiazzi, MD 334 78 86 14 88 jacques.orgiazzi@chu-lyon.fr
Bernard Conte-Delvox	Not yet recruiting
Marseille, France
Contact: Bernard Conte-Delvox, MD 334 91 38 65 97 bernard.conte-delvox@ap-hm.fr
CH de Montbrison	Recruiting
Montbrison, France, 42605
Contact: Luc Millot, MD 0033477967853 l.millot@ch-montbrison.fr
Principal Investigator: Luc Millot, MD
Jacques Bringer	Not yet recruiting
Montpellier, France
Contact: Jacques Bringer 334 67 33 83 82 j-bringer@chu-montpellier.fr
Marc Klein	Recruiting
Nancy, France
Contact: Marc Klein 333 83 15 34 31 m.klein@chu-nancy.fr
Michel Rodier	Recruiting
Nimes, France
Contact: Michel Rodier, MD 334 66 68 33 21 michel.rodier@chu-nimes.fr
Laurence Leenhardt	Recruiting
Paris, France
Contact: Laurence Leenhardt, MD 331 42 17 62 81 laurence.leenhardt@psl.ap-hop-paris.fr
Richard Marechaud	Recruiting
Poitiers, France
Contact: Richard Marechaud 335 49 44 43 80 r.marechaud@chu-poitiers.fr
Brigitte Delemer	Recruiting
Reims, France
Contact: Brigitte Delemer, MD 333 26 78 75 33 / 79 42 brigitte.delemer@wanadoo.fr
Claire Schvartz	Recruiting
Reims, France
Contact: Claire Schvartz, MD 333 26 50 43 21 claire.schvartz@reims.fnclcc.fr
Sub-Investigator: Béatrice Maes, MD
Sub-Investigator: Jean-Marie Pochart, MD
Didier Maugendre	Not yet recruiting
Rennes, France
Contact: Didier Maugendre, MD 332 99 26 71 42 didier.maugendre@chu-rennes.fr
Jean-Marc Kuhn	Recruiting
Rouen, France
Contact: Jean-Marc Kuhn, MD 332 32 88 90 82 jean-marc.kuhn@chu-rouen.fr
Bruno Estour	Recruiting
Saint-Etienne, France
Contact: Bruno Estour, MD 334 77 12 77 27 bruno.estour@chu-st-etienne.fr
Sub-Investigator: Luc Millot, MD
Centre Paul Strauss	Recruiting
Strasbourg, France, 67000
Contact: Olivier Schneegans, MD 0033388252428 oschneegans@strasbourg.fnclcc.fr
Principal Investigator: Olivier Schneegans, MD
Hopitaux Universitaires de Strasbourg	Recruiting
Strasbourg, France
Contact: Bernard Goichot, MD 333 88 12 75 93 bernard.goichot@chru-strasbourg.fr
Sub-Investigator: Jean-Louis Schlienger, MD
Sub-Investigator: Fabienne Grunenberger, MD
Sub-Investigator: Alain Pradignac, MD
Sub-Investigator: Stephane Vinzio, MD
Philippe Caron	Recruiting
Toulouse, France
Contact: Philippe Caron
Pierre Lecomte	Recruiting
Tours, France
Contact: Pierre Lecomte, MD 332 47 47 87.03 lecomte@med.univ-tours.fr

Sponsors and Collaborators

University Hospital, Strasbourg, France

Investigators

Principal Investigator:

Bernard Goichot, MD

Hopitaux Universitaires de Strasbourg

More Information

No publications provided

Responsible Party:	University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier:	NCT00213720 History of Changes
Other Study ID Numbers:	3463
Study First Received:	September 13, 2005
Last Updated:	April 19, 2012
Health Authority:	France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by University Hospital, Strasbourg, France:

Hyperthyroidism
atrial fibrillation
quality of life
radioiodine treatment

Additional relevant MeSH terms:

Atrial Fibrillation
Hyperthyroidism
Arrhythmias, Cardiac
Heart Diseases

Cardiovascular Diseases
Pathologic Processes
Thyroid Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on May 16, 2013

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