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Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema

This study has been completed.
Sponsor:
Information provided by:
Institute of Child Health
ClinicalTrials.gov Identifier:
NCT00144950
First received: September 2, 2005
Last updated: NA
Last verified: September 2005
History: No changes posted
  Purpose

This study will compare VATS versus chest drain insertion and urokinase in the treatment of childhood empema by a randomised prospective study.


Condition Intervention Phase
Empyema
 Drug: insertion of a chest drain with urokinase instillation
Procedure: primary video-assisted thorascopic surgery
 Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:

Drug Information available for: Urokinase
U.S. FDA Resources

Further study details as provided by Institute of Child Health:

Primary Outcome Measures:
  • length of hospital stay

Secondary Outcome Measures:
  • radiological changes at follow up

Estimated Enrollment: 60
  Eligibility

Ages Eligible for Study:   up to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • patients under the age of 16 referred to GOSH for management of empyema

Exclusion Criteria:

-

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00144950

Locations
United Kingdom
Great Ormond Street Hospital
London, United Kingdom
Sponsors and Collaborators
Institute of Child Health
Investigators
Principal Investigator: Adam Jaffe, Dr Great Ormond Street Hospital
  More Information

No publications provided by Institute of Child Health

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

ClinicalTrials.gov Identifier: NCT00144950     History of Changes
Other Study ID Numbers: 02AR04
Study First Received: September 2, 2005
Last Updated: September 2, 2005
Health Authority: United Kingdom: Research Ethics Committee

Additional relevant MeSH terms:
Empyema
Suppuration
Infection
Inflammation
Pathologic Processes

ClinicalTrials.gov processed this record on May 16, 2013