3527 studies found for:    "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Completed A Study of Trabectedin in Patients With Advanced Ovarian Cancer
Conditions: Ovarian Neoplasms;   Endocrine Gland Neoplasms;   Neoplasms by Site;   Neoplasms;   Ovarian Diseases;   Adnexal Diseases;   Genital Diseases, Female
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Completed A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients
Condition: HIV Infections
Interventions: Drug: Nelfinavir mesylate;   Drug: Lamivudine;   Drug: Filgrastim;   Drug: Stavudine;   Drug: Cyclophosphamide
4 Terminated
Has Results
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
Condition: Anaplastic Large Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: SGN-30
5 Completed A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer
Conditions: Breast Neoplasms;   Neoplasms;   Neoplasms by Site;   Breast Diseases;   Skin Diseases
Intervention: Drug: ET743
6 Recruiting Autologous Young Tumor-Infiltrating Lymphocytes (TIL) From People With Non-Small Cell Lung Cancer Following Preparative Chemotherapy
Conditions: Metastatic Non-Small Cell Lung Cancer;   Squamous Cell Carcinoma;   Advanced NSCLC;   Adenosquamous Carcinoma;   Adenocarcinomas
Interventions: Drug: Aldesleukin;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Biological: Young TIL
7 Active, not recruiting Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma
Condition: Lymphoma
Interventions: Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: gemcitabine hydrochloride;   Drug: ifosfamide;   Drug: mechlorethamine hydrochloride;   Drug: melphalan;   Drug: methotrexate;   Drug: mycophenolate mofetil;   Drug: prednisone;   Drug: procarbazine hydrochloride;   Drug: vincristine sulfate;   Drug: vinorelbine tartrate;   Procedure: allogeneic bone marrow transplantation;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: umbilical cord blood transplantation;   Radiation: total-body irradiation
8 Unknown  Lenalidomide Plus Melphalan as a Preparative Regimen for Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: A Phase 1 / 2 Study
Condition: Multiple Myeloma
Interventions: Drug: lenalidomide;   Drug: melphalan
9 Completed Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumors
Conditions: Leukemia, Myeloid, Acute;   Leukemia, Lymphocytic, Acute, T-Cell;   Juvenile Myelomonocytic Leukemia Lymphoblastic;   T-cell Lymphoblastic Lymphoma;   Myelodysplastic Syndrome
Interventions: Procedure: Haploidentical donor derived natural killer cell infusion;   Drug: Chemotherapy;   Device: CliniMACS
10 Terminated ABT-751 With Chemotherapy for Relapsed Pediatric ALL
Conditions: Recurrent Pediatric ALL;   Relapsed Pediatric ALL;   Acute Lymphoblastic Leukemia;   Refractory Pediatric ALL
Interventions: Drug: ABT-751;   Drug: dexamethasone;   Drug: PEG-asparaginase;   Drug: doxorubicin;   Drug: cytarabine;   Drug: methotrexate;   Drug: cyclophosphamide;   Drug: 6-thioguanine
11 Suspended Combination Chemotherapy in Treating Women With Stage III Breast Cancer
Condition: Breast Cancer
Interventions: Drug: CAF regimen;   Drug: CMF regimen;   Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: fluorouracil;   Drug: methotrexate;   Procedure: adjuvant therapy;   Procedure: conventional surgery;   Procedure: neoadjuvant therapy;   Radiation: radiation therapy
12 Terminated A Study Using Allogenic-Cytomegalovirus (CMV) Specific Cells for Glioblastoma Multiforme (GBM)
Condition: Glioblastoma Multiforme
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Biological: CMV Specific Cytotoxic T Lymphocytes (CTL)
13 Recruiting A Randomised Evaluation of Molecular Guided Therapy for Diffuse Large B-cell Lymphoma With Bortezomib
Condition: Lymphoma, Large B-Cell, Diffuse
Interventions: Drug: Rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone;   Drug: Bortezomib, rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone
14 Active, not recruiting Rituximab, Cyclophosphamide, and G-CSF Followed By Combination Chemotherapy in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant Followed By Rituximab and GM-CSF for Refractory Diffuse Large B-Cell Lymphoma
Condition: Lymphoma
Interventions: Biological: filgrastim;   Biological: rituximab;   Biological: sargramostim;   Drug: carmustine;   Drug: cyclophosphamide;   Drug: etoposide;   Procedure: adjuvant therapy;   Procedure: bone marrow ablation with stem cell support;   Procedure: peripheral blood stem cell transplantation
15 Completed Busulfan and Cyclophosphamide Followed by Bone Marrow Transplantation in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Conditions: Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
Interventions: Drug: busulfan;   Drug: cyclophosphamide;   Procedure: allogeneic bone marrow transplantation;   Procedure: bone marrow ablation with stem cell support;   Radiation: radiation therapy
16 Recruiting Stem Cell Transplantation for Patients With Multiple Myeloma
Condition: Myeloma
Interventions: Drug: G-CSF;   Drug: Plerixafor;   Procedure: Apheresis;   Drug: Melphalan;   Procedure: Stem cell re-infusion;   Drug: Basiliximab;   Device: CliniMACS CD25 microbeads and cell sorter
17 Completed
Has Results
Neoadjuvant Chemotherapy for Patients With Squamous Cell Carcinoma of the Penis
Condition: Penile Cancer
Interventions: Drug: Ifosfamide;   Drug: Paclitaxel (Taxol);   Drug: Cisplatin
18 Completed Diffuse Fibrotic Lung Disease
Conditions: Lung Diseases;   Pulmonary Fibrosis;   Sarcoidosis
Interventions: Drug: prednisone;   Drug: cyclophosphamide;   Drug: dapsone
19 Unknown  FCM Versus R-FCM Followed by R-Maintenance or Observation Only
Conditions: Lymphoma, Follicular;   Lymphoma, Low-Grade;   Lymphoma, Intermediate-Grade
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Mitoxantrone;   Drug: Rituximab;   Procedure: chemotherapy: FCM;   Procedure: chemotherapy: R-FCM;   Procedure: maintenance therapy: Rituximab
20 Recruiting Autologous Stem Cell Transplantation for Patients With Recurrent Nasopharyngeal Carcinoma
Condition: Recurrent Nasopharynx Carcinoma
Interventions: Drug: Etoposide phosphate;   Drug: Carboplatin;   Drug: Ifosfamide;   Procedure: Autologous Stem Cell Transplantation

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Indicates status has not been verified in more than two years