3521 studies found for:    "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Terminated
Has Results
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
Condition: Anaplastic Large Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: SGN-30
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Completed A Study of Trabectedin in Patients With Advanced Ovarian Cancer
Conditions: Ovarian Neoplasms;   Endocrine Gland Neoplasms;   Neoplasms by Site;   Neoplasms;   Ovarian Diseases;   Adnexal Diseases;   Genital Diseases, Female
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
4 Completed A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients
Condition: HIV Infections
Interventions: Drug: Nelfinavir mesylate;   Drug: Lamivudine;   Drug: Filgrastim;   Drug: Stavudine;   Drug: Cyclophosphamide
5 Completed A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer
Conditions: Breast Neoplasms;   Neoplasms;   Neoplasms by Site;   Breast Diseases;   Skin Diseases
Intervention: Drug: ET743
6 Terminated Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma
Conditions: Bone Cancer;   Ewing's Sarcoma
Interventions: Drug: Irinotecan;   Drug: Vincristine;   Drug: Temozolomide;   Drug: Doxorubicin;   Drug: Cytoxan;   Drug: Pegfilgrastim;   Drug: Mesna
7 Completed Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment
Conditions: Brain and Central Nervous System Tumors;   Lymphoma;   Metastatic Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: bortezomib;   Drug: temozolomide;   Other: pharmacological study
8 Recruiting Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer
Conditions: Chronic Myeloproliferative Disorders;   Graft Versus Host Disease;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms
Interventions: Biological: graft-versus-tumor induction therapy;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: mycophenolate mofetil;   Procedure: umbilical cord blood transplantation;   Radiation: radiation therapy
9 Unknown  Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma
Conditions: Lymphoma;   Neurotoxicity
Interventions: Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: prednisolone;   Drug: procarbazine hydrochloride;   Drug: vincristine sulfate;   Radiation: radiation therapy
10 Completed High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Combination Chemotherapy in Treating Women With High-Risk Breast Cancer
Condition: Breast Cancer
Interventions: Biological: filgrastim;   Drug: CMF regimen;   Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: epirubicin hydrochloride;   Drug: fluorouracil;   Drug: mesna;   Drug: methotrexate;   Drug: tamoxifen citrate;   Procedure: peripheral blood stem cell transplantation;   Radiation: low-LET electron therapy;   Radiation: low-LET photon therapy
11 Completed
Has Results
Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple Myeloma
Condition: Multiple Myeloma
Interventions: Drug: Myeloma Immunoglobulin Idiotype Vaccine;   Drug: Bortezomib;   Drug: Cyclophosphamide;   Drug: Cyclosporine;   Drug: Doxorubicin hydrochloride;   Drug: Etoposide;   Drug: Fludarabine phosphate;   Drug: Prednisone;   Drug: Vincristine Sulfate;   Drug: Methotrexate;   Biological: GMCSF (granulocyte macrophage colony stimulating factor);   Biological: GCSF (granulocyte colony stimulating factor)
12 Recruiting ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma
Condition: Osteosarcoma
Interventions: Drug: Mifamurtide arm;   Other: 3 drugs arm
13 Completed Combination Chemotherapy With Ketoconazole in Treating Patients With Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: Doxorubicin Hydrochloride;   Drug: Estramustine phosphate sodium;   Drug: Etoposide;   Drug: Ketoconazole;   Drug: Paclitaxel;   Drug: Vinblastine
14 Completed
Has Results
Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplant
Conditions: Breast Cancer;   Chronic Myeloproliferative Disorders;   Gestational Trophoblastic Tumor;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms;   Nausea and Vomiting;   Neuroblastoma;   Ovarian Cancer;   Testicular Germ Cell Tumor
Interventions: Drug: Aprepitant;   Drug: Cyclophosphamide;   Drug: Dexamethasone;   Drug: Granisetron hydrochloride
15 Completed Bevacizumab and Irinotecan or Bevacizumab and Temozolomide With Concomitant Radiotherapy for Primary Glioblastoma Multiforme (GBM)
Condition: Glioblastoma Multiforme
Interventions: Drug: bevacizumab and Irinotecan and radiotherapy;   Drug: Bevacizumab and Temozolomide and radiotherapy
16 Active, not recruiting A Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Unresectable or Metastatic Soft-tissue Sarcoma
Condition: Soft Tissue Sarcoma
Interventions: Drug: Palifosfamide Tris and Doxorubicin;   Drug: Doxorubicin
17 Completed Combination Chemotherapy in Patients With Advanced Urinary Tract Cancer
Conditions: Bladder Cancer;   Urethral Cancer
Interventions: Drug: cisplatin;   Drug: ifosfamide;   Drug: paclitaxel
18 Completed A Pilot Trial of AC (Adriamycin, Cyclophosphamide) Chemotherapy With G-CSF (Granulocyte Colony-Stimulating Factor) Followed by Infusional Taxol (Paclitaxel) as Adjuvant Treatment for High Risk Stage II and Stage III Breast Cancer Patients
Conditions: Breast Cancer;   Breast Neoplasms
Interventions: Drug: Adriamycin;   Drug: cyclophosphamide;   Drug: G-CSF;   Drug: paclitaxel
19 Terminated Cyclophosphamide and Filgrastim Followed By SCT in Patients With Chronic or Accelerated Phase Myelogenous Leukemia
Condition: Leukemia
Interventions: Drug: cyclophosphamide;   Drug: filgrastim;   Drug: recombinant interferon alfa;   Procedure: peripheral blood stem cell transplantation;   Procedure: radiation therapy
20 Completed Therapeutic Autologous Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Stage IV Melanoma
Conditions: Recurrent Melanoma;   Stage IV Melanoma
Interventions: Drug: cyclophosphamide;   Biological: therapeutic autologous lymphocytes;   Biological: aldesleukin;   Other: immunohistochemistry staining method;   Procedure: biopsy;   Other: laboratory biomarker analysis;   Other: immunologic technique;   Genetic: polymerase chain reaction

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Indicates status has not been verified in more than two years