3513 studies found for:    "Antineoplastic Agents, Alkylating"
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1 Completed A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients
Condition: HIV Infections
Interventions: Drug: Nelfinavir mesylate;   Drug: Lamivudine;   Drug: Filgrastim;   Drug: Stavudine;   Drug: Cyclophosphamide
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Completed A Study of Trabectedin in Patients With Advanced Ovarian Cancer
Conditions: Ovarian Neoplasms;   Endocrine Gland Neoplasms;   Neoplasms by Site;   Neoplasms;   Ovarian Diseases;   Adnexal Diseases;   Genital Diseases, Female
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
4 Terminated
Has Results
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
Condition: Anaplastic Large Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: SGN-30
5 Completed A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer
Conditions: Breast Neoplasms;   Neoplasms;   Neoplasms by Site;   Breast Diseases;   Skin Diseases
Intervention: Drug: ET743
6 Active, not recruiting Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT
Conditions: Acute Myeloid Leukemia (AML);   Myelodysplastic Syndrome (MDS)
Intervention: Drug: Treosulfan
7 Unknown  Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy
Conditions: Brain and Central Nervous System Tumors;   Thrombocytopenia
Interventions: Drug: temozolomide;   Genetic: comparative genomic hybridization;   Genetic: polymorphism analysis;   Other: laboratory biomarker analysis;   Other: pharmacological study;   Radiation: radiation therapy
8 Completed Epirubicin and Cyclophosphamide Compared With Epirubicin and Paclitaxel in Treating Women With Metastatic Breast Cancer
Condition: Breast Cancer
Interventions: Drug: cyclophosphamide;   Drug: epirubicin hydrochloride;   Drug: paclitaxel
9 Completed N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma
Conditions: Diarrhea;   Drug/Agent Toxicity by Tissue/Organ;   Neuroblastoma
Interventions: Drug: cefixime;   Drug: irinotecan hydrochloride;   Drug: temozolomide
10 Completed Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders
Conditions: Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Myelodysplastic-Myeloproliferative Diseases
Interventions: Biological: anti-thymocyte globulin;   Biological: filgrastim;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: melphalan;   Drug: methylprednisolone;   Procedure: umbilical cord blood transplantation;   Radiation: radiation therapy
11 Active, not recruiting A Phase 2, Multicenter, Open-label Study of MEDI-551 in Adults With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
Condition: Chronic Lymphocytic Leukemia (CLL)
Interventions: Drug: MEDI-551;   Drug: Rituximab;   Drug: Bendamustine
12 Completed PTK787/ZK 222584 in Combination With Temozolomide and Radiation in Patients With Glioblastoma Taking Enzyme-Inducing Anti-Epileptic Drugs
Condition: Glioblastoma
Interventions: Drug: PTK787/ZK 222584;   Drug: Temozolomide;   Procedure: Radiation Therapy
13 Active, not recruiting Reduced-Intensity Conditioning Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma
Condition: Refractory Multiple Myeloma
Interventions: Drug: fludarabine phosphate;   Drug: melphalan;   Radiation: total-body irradiation;   Drug: mycophenolate mofetil;   Drug: cyclosporine;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Other: laboratory biomarker analysis
14 Completed A Trial in Patients With Diffuse Large-B-cell Lymphoma Comparing Pixantrone Against Doxorubicin
Condition: Diffuse Large-Cell Lymphoma
Interventions: Drug: CPOP-R;   Drug: CHOP-R
15 Completed Chemotherapy Followed by Surgery in Treating Women With Stage II or Stage III Breast Cancer
Condition: Breast Cancer
Interventions: Biological: filgrastim;   Drug: CMF regimen;   Drug: docetaxel;   Drug: doxorubicin hydrochloride;   Drug: tamoxifen citrate;   Procedure: autologous bone marrow transplantation;   Procedure: surgical procedure;   Radiation: radiation therapy
16 Completed Chemotherapy Plus Radiation Therapy and Biological Therapy in Treating Patients With Hematologic Cancer
Conditions: Leukemia;   Lymphoma
Interventions: Drug: cyclophosphamide;   Procedure: allogeneic bone marrow transplantation;   Radiation: low-LET cobalt-60 gamma ray therapy
17 Unknown  Peripheral Stem Cell Transplant in Treating Patients With Metastatic Kidney Cancer
Condition: Kidney Cancer
Interventions: Biological: anti-thymocyte globulin;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: methotrexate;   Drug: mycophenolate mofetil
18 Unknown  Applying Pediatric Regimens to Younger Adult Patients With Acute Lymphoblastic Leukemia (ALL)
Condition: Lymphoblastic Leukemia, Acute
Interventions: Drug: Methotrexate;   Drug: Prednisolone;   Drug: Dexamethasone;   Drug: Vincristine;   Drug: Pirarubicin;   Drug: Cyclophosphamide;   Drug: L-asparaginase;   Drug: Cytarabine;   Drug: Hydrocortisone;   Drug: Mercaptopurine
19 Active, not recruiting
Has Results
Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma
Condition: Recurrent Glioblastoma
Interventions: Drug: Cediranib;   Drug: Lomustine Chemotherapy;   Drug: Placebo Cediranib
20 Completed
Has Results
A Study to Evaluate Two Different Regimens of VELCADE in Combination With Dexamethasone, Thalidomide and Cyclophosphamide (VDT vs VDTC) in Newly Diagnosed Multiple Myeloma
Condition: Multiple Myeloma
Interventions: Drug: bortezomib, dexamethasone, and thalidomide;   Drug: bortezomib, dexamethasone, thalidomide, and cyclophosphamide

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Indicates status has not been verified in more than two years