3519 studies found for:    "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Completed A Study of Trabectedin in Patients With Advanced Ovarian Cancer
Conditions: Ovarian Neoplasms;   Endocrine Gland Neoplasms;   Neoplasms by Site;   Neoplasms;   Ovarian Diseases;   Adnexal Diseases;   Genital Diseases, Female
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Terminated
Has Results
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
Condition: Anaplastic Large Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: SGN-30
4 Completed A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients
Condition: HIV Infections
Interventions: Drug: Nelfinavir mesylate;   Drug: Lamivudine;   Drug: Filgrastim;   Drug: Stavudine;   Drug: Cyclophosphamide
5 Completed A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer
Conditions: Breast Neoplasms;   Neoplasms;   Neoplasms by Site;   Breast Diseases;   Skin Diseases
Intervention: Drug: ET743
6 Completed Randomized Study Comparing Pre- and Postoperative Vs. Conventional Adjuvant Treatment in Receptor-Negative Patients
Condition: Early Stage Breast Cancer
Interventions: Drug: Cyclophosphamide;   Drug: Methotrexate;   Drug: Fluorouracil;   Drug: Epirubicine
7 Active, not recruiting UARK 2006-66, Total Therapy 3B: An Extension of UARK 2003-33 Total Therapy
Condition: Multiple Myeloma
Interventions: Drug: Bortezomib (Velcade);   Drug: Thalidomide;   Drug: Dexamethasone;   Drug: Melphalan;   Drug: Cisplatin;   Drug: Doxorubicin;   Drug: Cyclophosphamide;   Drug: Etoposide;   Drug: Filgrastim;   Drug: Lenalidomide
8 Completed
Has Results
S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: bicalutamide;   Drug: estramustine;   Drug: etoposide;   Drug: flutamide;   Drug: goserelin;   Drug: leuprolide;   Drug: nilutamide;   Drug: paclitaxel
9 Active, not recruiting Busulfan, Etoposide, and Total-Body Irradiation Followed by Autologous Stem Cell Transplant and Aldesleukin in Treating Patients With Acute Myeloid Leukemia in First Remission
Condition: Leukemia
Interventions: Biological: aldesleukin;   Biological: filgrastim;   Drug: busulfan;   Drug: cytarabine;   Drug: etoposide;   Drug: idarubicin;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: bone marrow transplantation;   Procedure: peripheral blood stem cell transplantation;   Radiation: total-body irradiation
10 Recruiting Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
Conditions: Hematopoietic Stem Cell Transplantation;   Solid Tumor;   Transplantation, Autologous
Interventions: Drug: Ifosfamide;   Drug: Etoposide phosphate;   Drug: Mesna;   Biological: Granulocyte colony-stimulating factor;   Drug: Busulfan;   Drug: Melphalan;   Drug: Thiotepa;   Biological: Autologous stem cell infusion;   Radiation: Radiation;   Drug: Caboplatin
11 Active, not recruiting Azacitidine With Rituximab, Vincristine, and Cyclophosphamide in Refractory Lymphoma
Conditions: Lymphoma;   Hodgkin Disease;   Lymphoma, Non-Hodgkin
Intervention: Drug: Azacitidine with rituximab, vincristine, and cyclophosphamide
12 Recruiting Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastoma
Conditions: Grade IV Astrocytoma;   Glioblastoma
Interventions: Drug: Temozolomide;   Drug: folinic acid at pharmacological dose is the escalated drug;   Radiation: High voltage radiation therapy (linear accelerator)
13 Recruiting Low Dose Cyclophosphamide +/-- Nintedanib in Advanced Ovarian Cancer
Conditions: Ovarian Cancer;   Fallopian Tube Cancer
Intervention: Drug: BIBF 1120
14 Active, not recruiting Bortezomib Plus ICE (BICE) Versus Standard ICE for Patients With Relapsed/Refractory Classical Hodgkin Lymphoma
Condition: Hodgkin's Lymphoma
Interventions: Drug: Bortezomib;   Drug: Ifosfamide;   Drug: Carboplatin;   Drug: Etoposide;   Drug: Neulasta (Pegfilgrastim);   Drug: Mesna
15 Recruiting Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma
Conditions: Advanced Cancers;   Lymphoma
Interventions: Drug: Azacitidine;   Drug: Vorinostat;   Drug: Gemcitabine;   Drug: Busulfan;   Drug: Melphalan;   Drug: Dexamethasone;   Other: Caphosol;   Drug: Glutamine;   Drug: Pyridoxine;   Drug: Rituximab
16 Active, not recruiting A Study in Recurrent Glioblastoma (GB)
Condition: Glioblastoma
Interventions: Drug: LY2157299 monohydrate;   Drug: Lomustine;   Drug: Placebo
17 Completed Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer
Conditions: Graft Versus Host Disease;   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms
Interventions: Drug: busulfan;   Drug: melphalan;   Drug: methotrexate;   Drug: tacrolimus;   Procedure: allogeneic bone marrow transplantation
18 Recruiting Bortezomib, Ifosfamide, Carboplatin, and Etoposide, With or Without Rituximab, in Treating Patients With Relapsed or Refractory AIDS-Related Non-Hodgkin Lymphoma
Condition: Lymphoma
Interventions: Biological: rituximab;   Drug: bortezomib;   Drug: carboplatin;   Drug: dexamethasone;   Drug: etoposide;   Drug: ifosfamide;   Genetic: polymerase chain reaction;   Genetic: western blotting
19 Completed Amifostine Followed by High Dose Chemotherapy in Treating Patients With Hematologic Cancer or Solid Tumors
Conditions: Breast Cancer;   Drug/Agent Toxicity by Tissue/Organ;   Lung Cancer;   Lymphoma;   Ovarian Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Biological: sargramostim;   Drug: amifostine trihydrate;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: etoposide
20 Completed Allogeneic Peripheral Stem Cell Transplant After Antithymocyte Globulin, High-Dose Melphalan, and Fludarabine in Treating Women With Metastatic Adenocarcinoma of the Breast
Condition: Breast Cancer
Interventions: Biological: anti-thymocyte globulin;   Biological: filgrastim;   Biological: graft-versus-tumor induction therapy;   Biological: therapeutic allogeneic lymphocytes;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: melphalan;   Drug: methotrexate;   Procedure: peripheral blood stem cell transplantation

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Indicates status has not been verified in more than two years