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3544 studies found for:    "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Completed A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients
Condition: HIV Infections
Interventions: Drug: Nelfinavir mesylate;   Drug: Lamivudine;   Drug: Filgrastim;   Drug: Stavudine;   Drug: Cyclophosphamide
2 Recruiting Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Immune System Diseases
Interventions: Drug: Cyclophosphamide;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Procedure: Allogeneic hematopoietic stem cell transplantation
3 Completed A Study of Trabectedin in Patients With Advanced Ovarian Cancer
Conditions: Ovarian Neoplasms;   Endocrine Gland Neoplasms;   Neoplasms by Site;   Neoplasms;   Ovarian Diseases;   Adnexal Diseases;   Genital Diseases, Female
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
4 Terminated
Has Results
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
Condition: Anaplastic Large Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: SGN-30
5 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
6 Completed A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer
Conditions: Breast Neoplasms;   Neoplasms;   Neoplasms by Site;   Breast Diseases;   Skin Diseases
Intervention: Drug: ET743
7 Recruiting Lenalidomide vs Placebo Maintenance Therapy Following Melphalan Prednisone Velcade® Induction Therapy in NDMM
Condition: Multiple Myeloma
Interventions: Drug: Lenalidomide;   Drug: Placebo
8 Not yet recruiting A Phase II Trial of Oncolytic Virotherapy by Systemic Administration of Edmonston Strain of Measles Virus
Condition: Multiple Myeloma
Intervention: Drug: MV-NIS
9 Completed Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer
Conditions: Breast Cancer;   Colorectal Cancer;   Kidney Cancer;   Lung Cancer;   Malignant Mesothelioma;   Pancreatic Cancer
Interventions: Biological: allogeneic tumor cell vaccine;   Biological: autologous tumor cell vaccine;   Biological: recombinant interferon alfa;   Biological: recombinant interferon gamma;   Biological: sargramostim;   Drug: cyclophosphamide
10 Terminated
Has Results
Study of Temozolomide to Treat Newly Diagnosed Brain Metastases
Condition: Brain Metastases
Intervention: Drug: Temozolomide
11 Recruiting Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Operable Patients
Condition: Sinonasal Tumors
Interventions: Drug: Cisplatin;   Drug: Docetaxel;   Drug: 5-fluorouracil;   Drug: Etoposide;   Drug: Adriamycin;   Drug: Ifosfamide;   Drug: Leucovorin;   Radiation: Radiotherapy - Patients needing Elective Nodal Volume (ENI);   Radiation: Radiotherapy - Patients not needing ENI;   Radiation: Radiotherapy - Patients needing curative neck irradiation
12 Active, not recruiting
Has Results
Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia
Conditions: Acute Lymphoblastic Leukemia;   Lymphoma, Lymphoblastic
Interventions: Drug: Etoposide, cytarabine, vincristine, dexamethasone;   Drug: methotrexate, teniposide, PEG-asparaginase;   Drug: mitoxantrone, cyclophosphamide, mercaptopurine, vinblastine;   Drug: L-asparaginase, erwinia asparaginase;   Procedure: chemotherapy, intrathecal chemotherapy, steroid therapy;   Procedure: Hematopoietic Stem Cell Transplant;   Procedure: Natural Killer (NK) Cell Transplant
13 Recruiting Sirolimus With Cyclophosphamide and Topotecan for Pediatric/Adolescent Relapsed and Refractory Solid Tumors
Conditions: Malignant Solid Tumor;   Childhood Solid Tumor
Intervention: Drug: Sirolimus, Cyclophosphamide, Topotecan
14 Completed Interleukin-12 Following Chemotherapy in Treating Patients With Refractory HIV-Associated Non-Hodgkin's Lymphoma
Condition: Lymphoma
Interventions: Biological: filgrastim;   Biological: recombinant interleukin-12;   Drug: etoposide;   Drug: ifosfamide
15 Recruiting Study of IPI-145 in Combination With Bendamustine, Rituximab or Bendamustine/Rituximab in Hematologic Malignancies
Conditions: Lymphoma;   Chronic Lymphocytic Leukemia;   Non-Hodgkin Lymphoma;   T-cell Lymphoma
Interventions: Drug: IPI-145;   Drug: Rituximab;   Drug: Bendamustine
16 Completed Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
Conditions: Brain Tumors;   Central Nervous System Tumors
Interventions: Biological: filgrastim;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: lomustine;   Drug: mesna;   Drug: vincristine sulfate;   Radiation: low-LET electron therapy;   Radiation: low-LET photon therapy
17 Unknown  CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors
Conditions: Polyarteritis Nodosa;   Microscopic Polyangiitis
Interventions: Drug: azathioprine;   Drug: cyclophosphamide
18 Completed Docetaxel, Doxorubicin, and Cyclophosphamide in Treating Women With Stage III Breast Cancer
Condition: Breast Cancer
Interventions: Drug: cyclophosphamide;   Drug: docetaxel;   Drug: doxorubicin hydrochloride;   Procedure: conventional surgery
19 Recruiting SCD-Haplo: A Phase II Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Procedure: Haploidentical Transplant;   Drug: Alemtuzumab;   Radiation: Total Body Irradiation;   Drug: Cyclophosphamide;   Drug: Sirolimus
20 Recruiting Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors
Conditions: Gastrinoma;   Glucagonoma;   Insulinoma;   Islet Cell Carcinoma;   Pancreatic Polypeptide Tumor;   Recurrent Islet Cell Carcinoma;   Somatostatinoma
Interventions: Drug: temozolomide;   Drug: capecitabine;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years